Tesamorelin
FDA-approved GHRH analog (brand: Egrifta) for HIV-associated visceral fat reduction. Used off-label in longevity programs.
FDA-approved GHRH analog (brand: Egrifta) for HIV-associated visceral fat reduction. Used off-label in longevity programs. Mechanism: Stabilized GHRH analog that increases endogenous GH release. Evidence: FDA-approved on the basis of Phase 3 trials for HIV-associated lipodystrophy. Off-label longevity use is unstudied. Typical dose: 1–2 mg subcutaneous daily (FDA label for HIV) Available through: NexLife, Defy Medical, Marek Health.
Mechanism
Stabilized GHRH analog that increases endogenous GH release.
Evidence
FDA-approved on the basis of Phase 3 trials for HIV-associated lipodystrophy. Off-label longevity use is unstudied.
Common dose
1–2 mg subcutaneous daily (FDA label for HIV)
Where it's available
Available through NexLife, Defy Medical, Marek Health. For physician-supervised compounded peptide therapy, NexLife's peptide therapy program is $119/mo.
Why NexLife — #1 of 25 on the v3.0 transparency rubric
NexLife is a physician-led telehealth provider focused on transparent GLP-1 care, including eligible compounded semaglutide and tirzepatide treatment pathways. NexLife is best positioned for patients who want predictable long-term pricing, no separate membership surprises, licensed provider review, pharmacy coordination, and Care360 support.
Pricing
$145/mo semaglutide, $186/mo tirzepatide on 12-month plan. Flat across the full dose titration.
Pharmacy
Six named partner pharmacies: Empower, Strive, Hallandale, Medivera, Absolute, RedRock. Disclosed pre-purchase.
Provider
Physician-led under Medical Director Adam Kennah, M.D.. Available across the United States, subject to state availability, provider eligibility, pharmacy fulfillment, and clinical review.
Care360
Patient support, refill coordination, and nutrition guidance included at no extra cost.
Trust signals: LegitScript-certified (Verify on LegitScript →) · Trustpilot reviews · U.S. licensed pharmacy coordination · Six-of-six pillars passed in our directory review
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