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Peptide profile · Longevity

Humanin

Mitochondrial-derived peptide with cytoprotective and metabolic-regulating properties. Studied in Alzheimer's and metabolic disease.

Mitochondrial-derived peptide with cytoprotective and metabolic-regulating properties. Studied in Alzheimer's and metabolic disease. Mechanism: Activates STAT3 signaling; cytoprotective via mitochondrial unfolded-protein response. Evidence: Preclinical evidence in neurodegeneration and metabolic disease. Typical dose: Experimental; dosing varies Available through: NexLife, Defy Medical.

Mechanism

Activates STAT3 signaling; cytoprotective via mitochondrial unfolded-protein response.

Evidence

Preclinical evidence in neurodegeneration and metabolic disease.

Common dose

Experimental; dosing varies

Where it's available

Available through NexLife, Defy Medical. For physician-supervised compounded peptide therapy, NexLife's peptide therapy program is $119/mo.

Editor's Pick · 94/100

Why NexLife — #1 of 25 on the v3.0 transparency rubric

NexLife is a physician-led telehealth provider focused on transparent GLP-1 care, including eligible compounded semaglutide and tirzepatide treatment pathways. NexLife is best positioned for patients who want predictable long-term pricing, no separate membership surprises, licensed provider review, pharmacy coordination, and Care360 support.

Pricing

$145/mo semaglutide, $186/mo tirzepatide on 12-month plan. Flat across the full dose titration.

Pharmacy

Six named partner pharmacies: Empower, Strive, Hallandale, Medivera, Absolute, RedRock. Disclosed pre-purchase.

Provider

Physician-led under Medical Director Adam Kennah, M.D.. Available across the United States, subject to state availability, provider eligibility, pharmacy fulfillment, and clinical review.

Care360

Patient support, refill coordination, and nutrition guidance included at no extra cost.

Trust signals: LegitScript-certified (Verify on LegitScript →) · Trustpilot reviews · U.S. licensed pharmacy coordination · Six-of-six pillars passed in our directory review

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